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| Published on:

October 17, 2025

Chicken Pot Pie Casserole is a warm and hearty dish perfect for family dinners. It carries the comforting flavors of traditional chicken pot pie, but it is easier to make. This casserole combines tender chicken, mixed vegetables, and a creamy sauce, topped with soft, buttery biscuits. It only takes about an hour to prepare and cook, making it a great meal for busy weeknights. With simple ingredients and straightforward steps, even beginner cooks can whip up this delightful dish with ease. Serve this casserole with a side salad for a complete meal everyone will love.

Why You’ll Love This Chicken Pot Pie Casserole

You will enjoy Chicken Pot Pie Casserole for its comforting and satisfying qualities. The warm, creamy filling brims with chicken and vegetables, while the biscuits provide a fluffy topping. It’s a great way to use leftover chicken, and it can feed a crowd. This casserole is also a one-dish meal, which means less cleanup. Children and adults alike will appreciate its delicious flavors. Plus, you can customize the ingredients to suit your tastes. It’s a fun dish that brings everyone together around the dinner table.

How to Make Chicken Pot Pie Casserole

Ingredients You’ll Need

2 cups cooked chicken, shredded
1 cup frozen mixed vegetables (peas, carrots, corn)
1 can cream of chicken soup
1 cup milk
1 teaspoon garlic powder
1 teaspoon onion powder
Salt and pepper to taste
1 can refrigerated biscuit dough
2 tablespoons butter, melted

Step-by-Step Directions

Preheat the oven to 375°F (190°C).
In a large mixing bowl, combine the shredded chicken, frozen vegetables, cream of chicken soup, milk, garlic powder, onion powder, salt, and pepper. Mix well.
Pour the mixture into a greased 9×13-inch baking dish.
Cut the biscuit dough into quarters and arrange evenly over the chicken mixture.
Brush the biscuits with melted butter.
Bake for 25-30 minutes, or until the biscuits are golden brown and the filling is bubbly.
Let cool for a few minutes before serving.

How to Serve Chicken Pot Pie Casserole

Serve Chicken Pot Pie Casserole hot from the oven. You can garnish each serving with fresh parsley for a pop of color. Pair it with a green salad or fresh bread for a complete meal. This dish is perfect for family dinners or casual gatherings and is sure to please everyone.

How to Store Chicken Pot Pie Casserole

To store leftovers, let the casserole cool completely. Transfer it to an airtight container and refrigerate. It will last up to three days. You can reheat it in the oven or microwave, adding a splash of milk if the filling becomes too thick.

Tips for the Best Chicken Pot Pie Casserole

To make the best Chicken Pot Pie Casserole, use leftover rotisserie chicken for extra flavor. You can switch out the mixed vegetables for your favorites, like green beans or broccoli. Ensure the biscuit topping is evenly spaced to cook consistently. Keeping an eye on the baking time will help avoid overcooking.

Recipe Variations

Feel free to change the cream of chicken soup to cream of mushroom for a different flavor. You can also add herbs like thyme or rosemary for a seasonal touch. If you want to cut back on calories, consider using low-fat biscuits and soup.

Frequently Asked Questions (FAQs)

Can I use fresh vegetables instead of frozen?
Yes, you can use fresh vegetables. Just make sure to chop them finely and cook them a bit before mixing them in.

Can I freeze Chicken Pot Pie Casserole?
Yes, you can freeze it. Just assemble the casserole without baking, cover it tightly, and store it in the freezer for up to three months.

How can I make this dish vegetarian?
You can easily make it vegetarian by substituting the chicken with plant-based protein and using vegetable broth instead of cream of chicken soup.